STUDY MEASURES PERFORMANCE OF AGE-ADJUSTED D-DIMER CUTOFF VALUE (MAR 2014)

BACKGROUND: D-dimer is a by-product of fibrin cross-linking that is produced during clot formation. Elevated D-dimer levels are associated with ongoing clot formation. As people age, their normal D-dimer levels increase. Because of this, the normal cutoff value for a D-dimer test (< 500 mcg/L) loses specificity in older patients. An age-adjusted cutoff value (calculated as age X 10) has been proposed as a means to increase the specificity of the D-dimer test in patients older than 50 years.

ADJUST-PE STUDY (2014) - PubMed abstract

StraightHealthcare analysis: