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SGLT2 INHIBITOR DOSING
  • NOTE: All dosing is for ADULT patients only
  • Dosing may vary for patients with liver problems, kidney problems, or other medical conditions



Drug Dosage form Typical dosage range Maximum Dose Food Generic/Price Other
Canagliflozin
(Invokana®)
Tablet
  • 100mg
  • 300mg
Starting
  • 100mg once daily
Maintenance
  • 100 - 300mg once daily
  • 300mg a day
  • Take before first meal of the day
NO/$$$$
  • Manufacturer recommends 300mg dose with UGT inducers. See Drug interactions for more details.
  • CrCl 45 - 59ml/min - dose should not exceed 100mg a day
  • CrCl < 45ml/min - DO NOT USE
  • See precautions for more

Drug Dosage form Typical dosage range Maximum Dose Food Generic/Price Other
Dapagliflozin
(Farxiga®)
Tablet
  • 5mg
  • 10mg
Starting
  • 5mg once daily
Maintenance
  • 5 - 10mg once daily
  • 10mg a day
  • Take in morning with or without food
NO/$$$$
  • DO NOT USE in patients with GFR < 60 ml/min. See precautions for details.

Drug Dosage form Typical dosage range Maximum Dose Food Generic/Price Other
Empagliflozin
(Jardiance®)
Tablet
  • 10mg
  • 25mg
Starting
  • 10mg once daily
Maintenance
  • 10 - 25mg once daily
  • 25mg a day
  • Take in morning with or without food
NO/$$$$
  • DO NOT USE in patients with GFR < 45 ml/min. See precautions for details.