FEATURES OF DIFFERENT ARTHRITIS SYNDROMES

^✝Reactive arthritis typically occurs 2 - 4 weeks after an infection with Shigella, Salmonella, Campylobacter, Chlamydia, or Strep throat

Reference [2,4,5,6] on **psoriasis and psoriatic arthritis**
Finding	Psoriatic arthritis	Rheumatoid arthritis	Lupus	Gout	Ankylosing spondylitis	Reactive arthritis	IBD-associated arthritis (Crohn's / UC)
Age of onset Male:Female	30 - 40s 1:1	35 - 50s 1:3	20 - 30s 1:9	30 - 60s 3:1	17 - 30s 3:1	20 - 30s 5:1	30s 2:1
Distal joints	Fingers and toes including DIP Asymmetric ≤ 4 joints	Fingers and toes, spares DIP Symmetric > 4 joints	Hands, wrists, knees Symmetric > 4 joints	Great toe, foot, ankle, knees, elbow Asymmetric < 4 joints	Lower limbs (30 - 50%) Asymmetric < 4 joints	Knees, ankles, hips Asymmetric < 4 joints	Hands and knees Asymmetric
Spine disease	Axial joints - 50% Sacroiliitis - 40%	Uncommon	Uncommon	Absent	100%	Sacroiliitis - 50% Back pain - 50%	30%
Enthesitis	30 - 50%, Plantar fascia and Achilles's tendon	Absent	Absent	Absent	Common	Common, Achilles tendon and plantar fascia	Uncommon
Dactylitis	40 - 50%	Absent	Absent	Uncommon	Uncommon	Common	Absent
HLA-B27 positive	40 - 50%	Not associated	Not associated	Not associated	90 - 95%	75%	30%
Eye disease	Uveitis - 8%	Dry eyes - 20%	Dry eyes - 15%	Absent	Uveitis - up to 30%	Conjunctivitis (common) Anterior uveitis - 25%	Uveitis - up to 7%
Other features	Psoriasis - 100% Nail disease - 85%	Positive RF and Anti-CCP	Positive ANA Joint disease is non-erosive	Elevated uric acid	Primarily affects the spine and pelvis	^✝Preceding infection Urethritis (common) Self-limited - 80%	Occurs in 10 - 20% of patients with IBD