FEATURES OF DIFFERENT ARTHRITIS SYNDROMES

  • Reactive arthritis typically occurs 2 - 4 weeks after an infection with Shigella, Salmonella, Campylobacter, Chlamydia, or Strep throat
  • Reference [2,4,5,6] on psoriasis and psoriatic arthritis
Finding Psoriatic arthritis Rheumatoid arthritis Lupus Gout Ankylosing spondylitis Reactive arthritis IBD-associated arthritis
(Crohn's / UC)
Age of onset
Male:Female
30 - 40s
1:1
35 - 50s
1:3
20 - 30s
1:9
30 - 60s
3:1
17 - 30s
3:1
20 - 30s
5:1
30s
2:1
Distal joints
Fingers and toes including DIP
Asymmetric
≤ 4 joints
Fingers and toes, spares DIP
Symmetric
> 4 joints
Hands, wrists, knees
Symmetric
> 4 joints
Great toe, foot, ankle, knees, elbow
Asymmetric
< 4 joints
Lower limbs (30 - 50%)
Asymmetric
< 4 joints
Knees, ankles, hips
Asymmetric
< 4 joints
Hands and knees
Asymmetric
Spine disease Axial joints - 50%
Sacroiliitis - 40%
Uncommon Uncommon Absent 100% Sacroiliitis - 50%
Back pain - 50%
30%
Enthesitis 30 - 50%, Plantar fascia and Achilles's tendon Absent Absent Absent Common Common, Achilles tendon and plantar fascia Uncommon
Dactylitis 40 - 50% Absent Absent Uncommon Uncommon Common Absent
HLA-B27 positive 40 - 50% Not associated Not associated Not associated 90 - 95% 75% 30%
Eye disease Uveitis - 8% Dry eyes - 20% Dry eyes - 15% Absent Uveitis - up to 30% Conjunctivitis (common)
Anterior uveitis - 25%
Uveitis - up to 7%
Other features Psoriasis - 100%
Nail disease - 85%
Positive RF and Anti-CCP Positive ANA
Joint disease is non-erosive
Elevated uric acid Primarily affects the spine and pelvis Preceding infection
Urethritis (common)
Self-limited - 80%
Occurs in 10 - 20% of patients with IBD