BILE ACID SEQUESTRANT DOSING

All dosing is for ADULTS unless otherwise specified
PRICING INFO


Drug Dosage form Dosing Generic/Price Food / Other
Cholestyramine

(Questran®)
Powder
  • 4 grams of cholestyramine resin per 9 grams of powder
  • Comes in 378 gram can (contains 42 doses of 4 grams of cholestyramine resin)
  • Comes in carton with 60 packets each with 4 grams of cholestyramine resin
High cholesterol / Pruritus
  • Starting: 4 grams of cholestyramine resin 1 - 2 times daily
  • Maintenance: 8 - 16 grams of cholestyramine resin a day given in 2 divided doses
  • Max: 24 grams of cholestyramine resin per day
  • Increase dose at intervals of 1 week
  • May be administered in 1 - 6 doses per day
  • See precautions for dosing in kidney and liver disease
YES/$$ FOOD
  • Best with meals, but may be taken at other times

OTHER
  • Mix with 2 - 6 oz of water or beverage
  • May also be mixed with applesauce or crushed pineapple
  • Color of powder may vary from batch to batch

Drug Dosage form Dosing Generic/Price Food / Other
Cholestyramine
light

(Questran Light®)
Powder
  • 4 grams of cholestyramine resin per 5.7 grams of powder
  • Comes in 239 gram can (contains 42 doses of 4 grams of cholestyramine resin)
  • Comes in carton with 60 packets each with 4 grams of cholestyramine resin
High cholesterol / Pruritus
  • Starting: 4 grams of cholestyramine resin 1 - 2 times daily
  • Maintenance: 8 - 16 grams of cholestyramine resin a day given in 2 divided doses
  • Max: 24 grams of cholestyramine resin per day
  • Increase dose at intervals of 1 week
  • May be administered in 1 - 6 doses per day
  • See precautions for dosing in kidney and liver disease
YES/$-$$ FOOD
  • Best with meals, but may be taken at other times

OTHER
  • Mix with 2 - 6 oz of water or beverage
  • May also be mixed with applesauce or crushed pineapple
  • Color of powder may vary from batch to batch

Drug Dosage form Dosing Generic/Price Food / Other
Colestipol
granules

(Colestid®)
Granules
  • Each packet or teaspoon contains 5 grams of colestipol
  • Comes in cartons of 30 or 90 packets
  • Comes in bottles of 300 grams and 500 grams

Flavored Granules
  • 7.5 grams of flavored granules contains 5 grams of colestipol
  • Comes in carton of 60 packets
  • Comes in bottle of 450 grams
High cholesterol
  • Starting: 5 grams of colestipol once or twice daily
  • Maintenance: 5 - 30 grams of colestipol a day given 1 or 2 divided doses
  • Max: 30 grams of colestipol per day
  • Increase dose in increments of 5 grams a day at intervals of 1 - 2 months
  • See precautions for dosing in kidney and liver disease
YES/$$ FOOD
  • Best with meals, but may be taken at other times

OTHER
  • Mix with ≥ 3 oz of liquid of choice
  • May also be mixed with cereals, soups, and fruits

Drug Dosage form Dosing Generic/Price Food / Other
Colestipol
tablet

(Colestid®)
Tablet
  • 1 gram
High cholesterol
  • Starting: 2 grams once or twice daily
  • Maintenance: 2 - 16 grams a day given in one or two divided doses
  • Max: 16 grams of colestipol per day
  • Increase dose in increments of 2 - 4 grams a day at intervals of 1 - 2 months
  • See precautions for dosing in kidney and liver disease
YES/$-$$ FOOD
  • Best with meals, but may be taken at other times

OTHER
  • Do not crush, cut, or chew tablets

Drug Dosage form Dosing Generic/Price Food / Other
Colesevelam
tablet

(Welchol™)
Tablet
  • 625 mg
High cholesterol
  • Dosing: 6 tablets once daily or 3 tablets twice a day
  • Max: 6 tablets a day
Type 2 diabetes
  • Dosing: 6 tablets once daily or 3 tablets twice a day
  • Max: 6 tablets a day

See precautions for dosing in kidney and liver disease
YES/$$$$ FOOD
  • Take with a meal and liquid

OTHER

Drug Dosage form Dosing Generic/Price Food / Other
Colesevelam
powder

(Welchol™)
Powder
  • Comes in packets of 1.875 grams (60 per carton) and 3.75 grams (30 per carton)
High cholesterol
  • Dosing: 3.75 grams once daily or 1.875 grams twice a day
  • Max: 3.75 grams a day
Type 2 diabetes
  • Dosing: 3.75 grams once daily or 1.875 grams twice a day
  • Max: 3.75 grams a day

See precautions for dosing in kidney and liver disease
NO/$$$$ FOOD
  • Take with a meal

OTHER
  • Mix with 4 - 8 oz of water, fruit juice, or diet drink