BILE ACID SEQUESTRANT DOSING

Drug	Dosage form	Dosing	Generic/Price	Food / Other
Cholestyramine (Questran®)	Powder 4 grams of cholestyramine resin per 9 grams of powder Comes in 378 gram can (contains 42 doses of 4 grams of cholestyramine resin) Comes in carton with 60 packets each with 4 grams of cholestyramine resin	High cholesterol / Pruritus Starting: 4 grams of cholestyramine resin 1 - 2 times daily Maintenance: 8 - 16 grams of cholestyramine resin a day given in 2 divided doses Max: 24 grams of cholestyramine resin per day Increase dose at intervals of 1 week May be administered in 1 - 6 doses per day See precautions for dosing in kidney and liver disease	YES/$$	FOOD Best with meals, but may be taken at other times OTHER Mix with 2 - 6 oz of water or beverage May also be mixed with applesauce or crushed pineapple Color of powder may vary from batch to batch

Drug	Dosage form	Dosing	Generic/Price	Food / Other
Cholestyramine light (Questran Light®)	Powder 4 grams of cholestyramine resin per 5.7 grams of powder Comes in 239 gram can (contains 42 doses of 4 grams of cholestyramine resin) Comes in carton with 60 packets each with 4 grams of cholestyramine resin	High cholesterol / Pruritus Starting: 4 grams of cholestyramine resin 1 - 2 times daily Maintenance: 8 - 16 grams of cholestyramine resin a day given in 2 divided doses Max: 24 grams of cholestyramine resin per day Increase dose at intervals of 1 week May be administered in 1 - 6 doses per day See precautions for dosing in kidney and liver disease	YES/$-$$	FOOD Best with meals, but may be taken at other times OTHER Mix with 2 - 6 oz of water or beverage May also be mixed with applesauce or crushed pineapple Color of powder may vary from batch to batch

Drug	Dosage form	Dosing	Generic/Price	Food / Other
Colestipol granules (Colestid®)	Granules Each packet or teaspoon contains 5 grams of colestipol Comes in cartons of 30 or 90 packets Comes in bottles of 300 grams and 500 grams Flavored Granules 7.5 grams of flavored granules contains 5 grams of colestipol Comes in carton of 60 packets Comes in bottle of 450 grams	High cholesterol Starting: 5 grams of colestipol once or twice daily Maintenance: 5 - 30 grams of colestipol a day given 1 or 2 divided doses Max: 30 grams of colestipol per day Increase dose in increments of 5 grams a day at intervals of 1 - 2 months See precautions for dosing in kidney and liver disease	YES/$$	FOOD Best with meals, but may be taken at other times OTHER Mix with ≥ 3 oz of liquid of choice May also be mixed with cereals, soups, and fruits

Drug	Dosage form	Dosing	Generic/Price	Food / Other
Colestipol tablet (Colestid®)	Tablet 1 gram	High cholesterol Starting: 2 grams once or twice daily Maintenance: 2 - 16 grams a day given in one or two divided doses Max: 16 grams of colestipol per day Increase dose in increments of 2 - 4 grams a day at intervals of 1 - 2 months See precautions for dosing in kidney and liver disease	YES/$-$$	FOOD Best with meals, but may be taken at other times OTHER Do not crush, cut, or chew tablets

Drug	Dosage form	Dosing	Generic/Price	Food / Other
Colesevelam tablet (Welchol™)	Tablet 625 mg	High cholesterol Dosing: 6 tablets once daily or 3 tablets twice a day Max: 6 tablets a day Type 2 diabetes Dosing: 6 tablets once daily or 3 tablets twice a day Max: 6 tablets a day See precautions for dosing in kidney and liver disease	YES/$$$$	FOOD Take with a meal and liquid OTHER

Drug	Dosage form	Dosing	Generic/Price	Food / Other
Colesevelam powder (Welchol™)	Powder Comes in packets of 1.875 grams (60 per carton) and 3.75 grams (30 per carton)	High cholesterol Dosing: 3.75 grams once daily or 1.875 grams twice a day Max: 3.75 grams a day Type 2 diabetes Dosing: 3.75 grams once daily or 1.875 grams twice a day Max: 3.75 grams a day See precautions for dosing in kidney and liver disease	NO/$$$$	FOOD Take with a meal OTHER Mix with 4 - 8 oz of water, fruit juice, or diet drink