• GT = Genotype; CP = Child-Pugh
HCV cure rates for Epclusa
GT No cirrhosis or CP A CP B/C
1 > 90% > 90%
2 > 90% > 90%
3 > 90% > 90%
4 > 90% > 90%
5 > 90% N/A
6 > 90% N/A


Reference [2]
Side effect Epclusa® for 12 weeks
N=624
Placebo for 12 weeks
N=116
Headache 29% 28%
Fatigue 20% 20%
Nasopharyngitis 13% 10%
Nausea 12% 11%
Insomnia 8% 9%
Diarrhea 8% 7%
Asthenia 7% 8%
Arthralgia 6% 8%
Cough 6% 3%

Reference [1]
Side effect Epclusa® Placebo
Lipase elevations
> 3 X ULN
3% 1%
Rash 2% 1%
Depression 1% 0%
CK elevations
> 10 X ULN
1% 0%