FIBRATE DOSING





Antara® (Fenofibrate micronized)

Dosage forms

Capsule
  • 43 mg
  • 90 mg
  • 130 mg

Dosing

Primary hypercholesterolemia and mixed dyslipidemia
  • Dosing: 130 mg once daily
  • Max: 130 mg once daily
  • Do not open, crush, dissolve, or chew capsules
  • Recheck lipids in 4 - 8 weeks
  • May take without regard to food
Severe Hypertriglyceridemia
  • Dosing: 43 - 130 mg once daily
  • Max: 130 mg once daily
  • Do not open, crush, dissolve, or chew capsules
  • Recheck lipids in 4 - 8 weeks
  • May take without regard to food
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 43 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

  • 90 mg dose: YES/$$$$
  • 43 and 130 mg dose: YES/$

Fenoglide® (Fenofibrate)

Dosage forms

Tablet
  • 40 mg
  • 120 mg

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 120 mg once daily
  • Max: 120 mg once daily
  • Do not crush, dissolve, or chew tablets
  • Recheck lipids in 4 - 8 weeks
  • Take with food to increase absorption
Severe Hypertriglyceridemia
  • Dosing: 40 - 120 mg once daily
  • Max: 120 mg once daily
  • Do not crush, dissolve, or chew tablets
  • Recheck lipids in 4 - 8 weeks
  • Take with food to increase absorption
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 40 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

  • 40 mg - YES/$$
  • 120 mg - YES/$$$$

Lipofen® (Fenofibrate)

Dosage forms

Capsule
  • 50 mg
  • 150 mg

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 150 mg once daily
  • Max: 150 mg once daily
  • Do not open, crush, dissolve, or chew capsules
  • Recheck lipids in 4 - 8 weeks
  • Take with food to increase absorption
Severe Hypertriglyceridemia
  • Dosing: 50 - 150 mg once daily
  • Max: 150 mg once daily
  • Do not open, crush, dissolve, or chew capsules
  • Recheck lipids in 4 - 8 weeks
  • Take with food to increase absorption
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 50 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

- YES/$$-$$$

Lofibra® capsule (Fenofibrate micronized)

Dosage forms

Capsule
  • 67 mg
  • 134 mg
  • 200 mg

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 200 mg once daily
  • Max: 200 mg once daily
  • Take with meals to increase absorption
Severe Hypertriglyceridemia
  • Dosing: 67 - 200 mg once daily
  • Max: 200 mg once daily
  • Take with meals to increase absorption
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 67 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

- YES/$

Lofibra® tablet (Fenofibrate)

Dosage forms

Tablet
  • 54 mg
  • 160 mg

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 160 mg once daily
  • Max: 160 mg once daily
  • May take without regard to food
Severe Hypertriglyceridemia
  • Dosing: 54 - 160 mg once daily
  • Max: 160 mg once daily
  • May take without regard to food
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 54 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

- YES/$

Tricor® (Fenofibrate)

Dosage forms

Tablet
  • 48 mg
  • 145 mg

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 145 mg once daily
  • Max: 145 mg once daily
  • May take without regard to food
Severe hypertriglyceridemia
  • Dosing: 48 - 145 mg once daily
  • Max: 145 mg once daily
  • May take without regard to food
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 48 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

- YES/$

Triglide® (Fenofibrate)

Dosage forms

Tablet
  • 160 mg

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 160 mg once daily
  • Max: 160 mg once daily
  • Do not crush, break, dissolve, or chew tablets
  • Recheck lipids in 8 weeks
  • May take without regard to food
Severe Hypertriglyceridemia
  • Dosing: 160 mg once daily
  • Max: 160 mg once daily
  • Do not crush, break, dissolve, or chew tablets
  • Recheck lipids in 8 weeks
  • May take without regard to food
Kidney disease
  • CrCl ≤ 89 ml/min - DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

- NO/$$$$

Trilipix® (Choline fenofibrate | Fenofibric acid)

Dosage forms

Capsule, delayed-release
  • 45 mg
  • 135 mg
  • Each capsule contains choline fenofibrate, equivalent to 45 mg or 135 mg of fenofibric acid

Dosing

Primary hypercholesterolemia or mixed dyslipidemia
  • Dosing: 135 mg once daily
  • Max: 135 mg once daily
  • Do not open, crush, dissolve, or chew capsules
  • Recheck lipids in 4 - 8 weeks
  • May take without regard to food
Severe Hypertriglyceridemia
  • Dosing: 45 - 135 mg once daily
  • Max: 135 mg once daily
  • Do not open, crush, dissolve, or chew capsules
  • Recheck lipids in 4 - 8 weeks
  • May take without regard to food
Kidney disease
  • CrCl 30 - 89 ml/min: starting dose is 45 mg/day. Titrate as tolerated.
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in active liver disease.

Generic / Price

- YES/$

Lopid® (Gemfibrozil)

Dosage forms

Tablet
  • 600 mg

Dosing

High cholesterol
  • Dosing: 600 mg twice daily
  • Max: 600 mg twice daily
  • Take 30 minutes before the morning and evening meal
Severe Hypertriglyceridemia
  • Dosing: 600 mg twice daily
  • Max: 600 mg twice daily
  • Take 30 minutes before the morning and evening meal
Kidney disease
  • CrCl 30 - 89 ml/min: has not been studied
  • CrCl < 30 ml/min: DO NOT USE
Liver disease
  • Has not been studied. Contraindicated in liver disease.

Generic / Price

- YES/$










Pricing legend
  • $ = 0 - $50
  • $$ = $51 - $100
  • $$$ = $101 - $150
  • $$$$ = > $150
  • Pricing based on one month of therapy at standard dosing in an adult
  • Pricing based on information from GoodRX.com®
  • Pricing may vary by region and availability