SJÖGREN'S SYNDROME






















  • Reference [3]
ACR 2012 proposed criteria for diagnosing SS
SS diagnosis - patients with symptoms consistent with SS (dry mouth and dry eyes) must meet 2 of the following 3 criteria:
Criteria 1: Positive serology
  • Positive serology defined as the presence of at least one of the following:
    • Positive serum anti-SSA/Ro
    • Positive serum anti-SSB/La
    • Combination of positive rheumatoid factor and ANA titer ≥ 1:320
Criteria 2: Positive salivary gland biopsy
  • Labial salivary gland biopsy exhibiting focal lymphocytic sialadenitis with a focus score ≥ 1 focus/4mm2
Criteria 3: Positive keratoconjunctivitis sicca (dry eyes) test
  • Keratoconjunctivitis sicca with ocular staining score ≥ 3
  • Assuming that individual is not currently using daily eye drops for glaucoma and has not had corneal surgery or cosmetic eyelid surgery in the last 5 years