TOPICAL DERMATOLOGIC MEDICATIONS




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ACNE - RETINOIC ACIDS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Adapalene Differin®
(0.1% gel available OTC)		 Cream 0.1% 45 g Once daily at bedtime YES / $$
Gel 0.1% 45 g Once daily at bedtime YES / $$
Gel 0.3% 45 g tube and pump Once daily at bedtime YES / $$
Lotion 0.1% 2 oz Once daily at bedtime NO / $$$$
Tretinoin Retin-A®
Avita®		 Cream 0.025% 20 g, 45 g Once daily at bedtime YES / $
Tretin-X® Cream 0.0375% 35 g Once daily at bedtime NO / $$$$
Retin-A® Cream 0.05% 20 g, 45 g Once daily at bedtime YES / $
Tretin-X® Cream 0.075% 35 g Once daily at bedtime NO / $$$$
Retin-A® Cream 0.1% 20 g, 45 g Once daily at bedtime YES / $
Retin-A® Gel 0.01% 15 g, 45 g Once daily at bedtime YES / $
Retin-A® Gel 0.025% 15 g, 45 g Once daily at bedtime YES / $
Retin-A Micro® Gel 0.04% 20 g, 45 g tube
50 g pump		 Once daily at bedtime YES / $$-$$$$
Atralin® Gel 0.05% 45 g Once daily at bedtime YES / $$-$$$
Retin-A Micro® Gel 0.08% 50 g pump Once daily at bedtime NO / $$$$
Retin-A Micro® Gel 0.1% 20 g, 45 g tube
50 g pump		 Once daily at bedtime YES / $$
Altreno™ Lotion 0.05% 45 g tube
50 g pump		 Once daily NO / $$$
Trifarotene Aklief® Cream 0.005% 30 g, 45 g, 75 g pump Once daily at bedtime NO / $$$$
Tazarotene
(Do not use in pregnancy)		 Tazorac®(Also approved for psoriasis) Cream 0.1% 30 g, 60 g Once daily at bedtime YES / $$$
Gel 0.1% 30 g, 100 g Once daily at bedtime YES / $$$
Arazlo® Lotion 0.045% 45 g Once daily NO / $$$$
Fabior® Foam 0.1% 50 g, 100 g Once daily at bedtime NO / $$$$


ACNE - TOPICAL ANTIBIOTICS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Azelaic acid Azelex® Cream 20% 30 g, 50 g Twice daily NO / $$$$
Benzoyl peroxide
(sold OTC)		 Clearasil®
Proactiv®
Oxy®
many others		 Cream
Lotion
Solution
Gel		 10%, 5%, 2.5%,
many others		 various Varies by product YES / $
Clindamycin Evoclin® Foam, aerosol 1% 50 g, 100 g Once daily YES / $$-$$$
Cleocin T® Gel 1% 30 g, 60 g Twice daily YES / $
Clindagel® Gel 1% 40 ml, 75 ml Once daily YES / $
Cleocin T® Lotion 1% 60 ml Twice daily YES / $
Cleocin T®
Clinda-Derm®		 Solution 1% 30 ml, 60 ml Twice daily YES / $
Clindets®
Cleocin®		 Swab 1% 60 pledgets Twice daily YES / $
Dapsone Aczone® Gel 5% 30 g, 60 g, 90 g tube Twice daily YES / $$$
Aczone® Gel 7.5% 30 g, 60 g, 90 g pump Once daily YES / $$$$
Erythromycin Erygel® Gel 2% 30 g, 60 g Once or twice a day YES / $-$$
Akne-Mycin® Ointment 2% 25 g Twice daily NO / $$$
Eryderm®
Erythro-statin®
Erythra-Derm®
C-Solve-2®		 Solution 2% 60 ml Twice daily YES / $
Swabs 2% 60 pledgets Twice daily YES / $
Minocycline Amzeeq® Foam 4% 30 g can Once daily at bedtime NO / $$$$
Sulfacetamide Klaron® Lotion 10% 4 oz Twice daily YES / $$


ACNE - TOPICAL ANTIANDROGEN
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Clascoterone Winlevi® Cream 1% 60 g Apply twice daily NO / $$$$
Studies


ACNE - COMBINATION PRODUCTS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Adapalene +
Benzoyl peroxide		 EpiDuo® Gel 0.1% / 2.5% 45 g tube
45 g pump		 Once daily YES / $
EpiDuo® Forte Gel 0.3% / 2.5% 15 g, 30 g, 45 g, 60 g, 70 g pump Once daily YES / $-$$$
Benzoyl peroxide +
Clindamycin		 Acanya® Gel 2.5% / 1.2% 50 g pump Once daily YES / $$
Benzaclin® Gel 5% / 1% 25 g jar
35 g, 50 g pump		 Twice daily YES / $$$
Duac®
Neuac®		 Gel 5% / 1.2% 45 g Once daily YES / $
Onexton® Gel 1.2% / 3.75% 50 g pump Once daily NO / $$$$
Benzoyl peroxide +
Erythromycin		 Benzamycin® Gel 5% / 3% 46.6 g jar Twice daily YES / $$
Benzamycin Pak® Gel 5% / 3% 60 pouches Twice daily NO / $$$$
Clindamycin +
Tretinoin		 Ziana® Gel 1.2% / 0.025% 30 g, 60 g Once daily YES / $$$$
Veltin® Gel 1.2% / 0.025% 30 g, 60 g Once daily NO / $$$$
Tretinoin +
Benzoyl peroxide		 Twyneo® Cream 0.1% / 3% 30 g pump Once daily NO / $$$$


ACTINIC KERATOSIS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Diclofenac Solaraze® Gel 3% 100 g Apply twice daily for 60 to 90 days YES / $
Fluorouracil Carac® Cream 0.5% 30 g Once daily up to 4 weeks YES / $$$$
Efudex® Cream 5% 40 g Twice daily for 2 - 4 weeks YES / $
Solution 2% 10 ml, 25 ml Twice daily for 2 - 4 weeks YES / $
Solution 5% 10 ml, 25 ml Twice daily for 2 - 4 weeks YES / $-$$
Fluoroplex® Cream 1% 30 g Twice daily for 2 - 6 weeks NO / $$$$
Tolak® Cream 4% 40 g Once daily for up to 4 weeks NO / $$$$
Imiquimod Aldara®(Also approved for genital warts) Cream 5% Single-use packet. Comes in box of 12 or 24 packets. Two times a week for 16 weeks YES / $ (#24)
Zyclara®(Also approved for genital warts) Cream 2.5% 7.5 g pump Apply once daily for 2 weeks.Take 2 weeks off, then reapply for 2 weeks. Leave on for 8 hours at a time. NO / $$$$
Cream 3.75% 7.5 g pump,
Box of 28 packets		 Apply once daily for 2 weeks. Take 2 weeks off, then reapply for 2 weeks. Leave on for 8 hours at a time. YES / $$$$
Ingenol mebutate Picato® Gel 0.015%
(for face or scalp)		 3 tubes Once daily for 3 days NO / $$$$
Gel 0.05%
(for trunk and extremities)		 2 tubes Once daily for 2 days NO / $$$$
Tirbanibulin Klisyri® Ointment 1% Single-use packet.
Comes in box with 5 packets.		 Apply 1 packet to face or scalp once daily for 5 days NO / $$$$
Studies


ANTIBIOTICS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Mupirocin Bactroban® Ointment 2% 22 g Two to three times a day YES / $
Cream 2% 15 g, 30 g Three times a day YES / $$
Ointment, nasal 2% 1g single use tubes Twice daily NO / $$$
Centany® Ointment 2% 30 g tube Three times a day NO / $$$$
Ozenoxacin Xepi® Cream 1% 30 g Twice daily for 5 days NO / $$$$
Retapamulin Altabax® Ointment 1% 15 g, 30 g Twice daily NO / $$$$


ANTIFUNGALS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Butenafine Mentax® Cream 1% 15 g, 30 g Once daily for 2 weeks
(Tinea versicolor)		 NO / $$$$
Lotrimin Ultra®
(Available OTC)		 Cream 1% 12 g 1 - 2 times daily NO / $
A number of OTC products Cream 1% Various sizes 1 - 2 times daily YES / $
Ciclopirox Loprox® Cream 0.77% 15 g, 30 g, 90 g Twice daily YES / $
Gel 0.77% 30 g, 45 g, 100 g Twice daily YES / $
Suspension 0.77% 30 ml, 60 ml Twice daily YES / $
Clotrimazole Lotrimin®(Available OTC) Cream 1% RX - 15 g, 30 g, 45 g
OTC - various sizes		 Twice daily YES / $
Mycelex®(Available OTC) Solution 1% RX - 10 ml, 30 ml
OTC - various sizes		 Twice daily YES / $
Econazole Ecoza® Foam 1% 70 g can Apply once daily
(Tinea pedis)		 NO / $$$$
Spectazole® Cream 1% 15 g, 30 g, 85 g 1 - 2 times daily YES / $
Ketoconazole Ketozole® Cream 2% 15 g, 30 g, 60 g Once daily YES / $
Nizoral® Shampoo 2% 4 oz (120 ml) One application
(Tinea versicolor)		 YES / $
Miconazole A number of OTC products Cream 2% Various sizes Twice daily YES / $
Lotrimin® AF(Available OTC) Spray 2% 4.6 oz Once daily NO / $
Nystatin Mycostatin® Cream 100,000 U/g 15 g, 30 g Twice daily YES / $
Ointment 100,000 U/g 15 g, 30 g Twice daily YES / $
Nyamyc® Powder 100,000 U/g 15 g, 30 g, 60 g Apply 2 - 3 times daily YES / $
Nystop® Powder 100,000 U/g 15 g, 30 g, 60 g Apply 2 - 3 times daily YES / $
Oxiconazole Oxistat® Cream 1% 30 g, 60 g, 90 g 1 - 2 times daily YES / $$$
Lotion 1% 30 ml, 60 ml 1 - 2 times daily NO / $$$$
Selenium sulfide Selseb® Lotion 2.5% 4 oz (118 ml) Once daily for 7 days
(Tinea versicolor)		 YES / $
Shampoo 2.25% 6 oz (180 ml) Once daily for 7 days
(Tinea versicolor)		 YES / $
Sertaconazole Ertaczo® Cream 2% 60 g Twice daily for 4 weeks
(Tinea pedis)		 NO / $$$$
Terbinafine Lamisil®(Available OTC) Cream 1% 12 g 1 - 2 times daily YES / $
Gel 1% 12 g 1 - 2 times daily NO / $
Spray 1% 125 ml 1 - 2 times daily NO / $


ANTIFUNGAL / STEROID COMBINATIONS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Clotrimazole +
betamethasone dipropionate		 Lotrisone® Cream 1% / 0.05% 15 g, 45 g Twice a day YES / $
Lotion 1% / 0.05% 30 ml Twice a day YES / $$
Nystatin +
triamcinolone acetonide		 Mykacet® Cream 100000 unit / 0.1% 15 g, 30 g, 60 g Twice a day YES / $
Ointment 100000 unit / 0.1% 15 g, 30 g, 60 g Twice a day YES / $


ANTIVIRALS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Acyclovir Zovirax® Cream
(herpes labialis)		 5% 5 g 5 times a day for 4 days NO / $$$$
Ointment
(genital herpes)		 5% 15 g, 30 g 6 times a day for 7 days YES / $
Acyclovir + hydrocortisone Xerese® Cream
(herpes labialis)		 5% / 1% 5 g 5 times a day for 5 days NO / $$$$
Penciclovir Denavir® Cream
(herpes labialis)		 1% 5 g Apply every 2 hours while awake for 4 days YES / $$$$


DERMATITIS / ECZEMA - CALCINEURIN INHIBITORS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Pimecrolimus Elidel® Cream 1% 30 g, 60 g, 100 g Twice daily YES / $$
Tacrolimus Protopic® Ointment 0.03% 30 g, 60 g, 100 g Twice daily YES / $$
Ointment 0.1% 30 g, 60 g, 100 g Twice daily YES / $$


DERMATITIS / ECZEMA - JANUS KINASE INHIBITOR
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Ruxolitinib Opzelura® Cream 1.5% 60 g, 100 g Twice daily on up to 20% of body surface area NO / $$$$
Studies


DERMATITIS / ECZEMA - PDE-4 INHIBITOR
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Crisaborole Eucrisa® Ointment 2% 60 g, 100 g Twice daily NO / $$$$
Studies


HYPERHIDROSIS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Aluminum chloride Drysol® Solution 20% 35 ml, 37.5 ml, 60 ml Once daily at bedtime. Wash off in morning. Once excessive sweating has stopped, may decrease to 1 - 2 times a week or as needed. NO / $
Glycopyrronium Qbrexza® Solution 2.4% 30 pads Apply to underarm once daily NO / $$$$


PSORIASIS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Anthralin Zithranol-RR™ Cream 1.2% 45 g Apply once daily
Titrate contact time		 NO / $$$$
Zithranol™ Shampoo 1% 85 g Apply 3 - 4 times a week
Rinse after 3 - 5 minutes		 NO / $$$$
Calcipotriene Dovonex® Cream 0.005% 60 g, 120 g Twice daily YES / $$$
Ointment 0.005% 60 g, 120 g Once or twice daily YES / $$$
Solution 0.005% 60 ml Apply to scalp twice daily YES / $$-$$$
Sorilux® Foam 0.005% 60 g, 120 g Twice daily NO / $$$$
Calcipotriene +
betamethasone dipropionate		 Wynzora® Cream 0.005% / 0.064% 60 g Once daily for up to 8 weeks NO / $$$$
Enstilar® Foam 0.005% / 0.064% 60 g, 120 g Once daily for up to 4 weeks NO / $$$$
Taclonex® Ointment 0.005% / 0.064% 60 g, 100 g Once daily for up to 4 weeks YES / $$$$
Suspension 0.005% / 0.064% 60 g, 120 g Once daily for up to 8 weeks YES / $$$$
Calcitriol Vectical® Ointment 3 mcg/g 100 g Twice daily YES / $$$$
Halobetasol propionate + tazarotene
(Do not use in pregnancy)		 Duobrii® Lotion 0.01% / 0.045% 100 g Once daily NO / $$$$
Salicylic acid Keralyt® Gel 6% 40 g, 100 g Apply to scalp as directed
Wash off after 10 - 20 minutes		 YES / $
Salex® Cream 6% 454 g Apply at night and wash off in AM YES / $
Lotion 6% 273 ml Apply at night and wash off in AM YES / $
Shampoo 6% 177 ml Wet hair, apply, lather and rinse YES / $
Salvax® Foam 6% 70 g, 200 g Apply twice daily YES / $
Tapinarof Vtama® Cream 1% 60 g Once daily NO / $$$$
Tazarotene
(Do not use in pregnancy)		 Tazorac®(Also approved for acne) Cream 0.05% 30 g, 60 g Once daily in the evening NO / $$$$
Cream 0.1% 30 g, 60 g Once daily in the evening YES / $$$
Gel 0.05% 30 g, 100 g Once daily in the evening NO / $$$$
Gel 0.1% 30 g, 100 g Once daily in the evening YES / $$$
Studies


  • ✝A number of manufactures make sulfacetamide-sulfur products. These medications are not FDA-approved and are therefore not listed in the FDA's Orange Book.
ROSACEA
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Azelaic acid Finacea® Gel 15% 50 g Twice daily YES / $$
Foam 15% 50 g can Twice daily NO / $$$$
Brimonidine Mirvaso® Gel 0.33% 30 g, 45 g tube
30 g pump		 Once daily NO / $$$$
Benzoyl peroxide Epsolay® Cream 5% 30 g pump Once daily NO / $$$$
Ivermectin Soolantra® Cream 1% 30 g, 45 g, 60 g Once daily NO / $$$$
Metronidazole Metrocream® Cream 0.75% 45 g Twice daily YES / $$-$$$
Noritate® Cream 1% 60 g Once daily NO / $$$$
Metrogel® Gel 0.75% 45 g Twice daily YES / $
Metrogel® Gel 1% 60 g tube
55 g pump		 Once daily YES / $$
MetroLotion® Lotion 0.75% 2 oz Twice daily YES / $$-$$$
Minocycline Zilxi™ Foam 1.5% 30 g can Once daily at bedtime NO / $$$$
Oxymetazoline Rhofade® Cream 1% 30 g, 60 g tube
30 g, 60 g pump		 Once daily NO / $$$$
Sulfacetamide sodium +
sulfur✝		 Avar-E® Cream 10% / 5% 45 g tube
2 oz bottle		 One to three times a day NO / $$$$
Avar-LS® Cleanser 10% / 2% 8 oz bottle One to two times a day NO / $$$$
Prascion® Cleanser 10% / 5% 6 oz, 12 oz One to two times a day NO / $$$$

SEBORRHEIC DERMATITIS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Ciclopirox Loprox® Gel 0.77% 30 g, 45 g, 100 g Twice daily YES / $
Shampoo 1% 120 ml Twice weekly for 4 weeks YES / $
Ketoconazole Extina® Foam 2% 50 g, 100 g can Twice daily YES / $$$
Ketozole® Cream 2% 15 g, 30 g, 60 g Twice daily YES / $
Nizoral® Shampoo 2% 4 oz (120 ml) Twice weekly for 2 - 4 weeks YES / $
Nizoral® A-D(Available OTC) Shampoo 1% 4 oz, 7 oz Twice weekly for up to 8 weeks NO / $
Xolegel® Gel 2% 45 g Once daily NO / $$$$
Selenium sulfide Selseb® Lotion 2.5% 4 oz (118 ml) Treat: Twice weekly X 2 weeks
Prevent: 1 - 4 times/month		 YES / $
Shampoo 2.25% 6 oz (180 ml) Treat: Twice weekly X 2 weeks
Prevent: 1 - 4 times/month		 YES / $
Selsun blue®
Head and shoulders®
(Available OTC)		 Shampoo 1% Various sizes Twice weekly YES / $


WRINKLES, HYPERPIGMENTATION - RETINOIC ACIDS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Tretinoin Renova® Cream 0.02% 20 g, 40 g, 60 g tube
44 g pump		 Once daily at bedtime NO / $$$$
Renova®
Refissa®		 Cream 0.05% 20 g, 40 g, 60 g Once daily at bedtime YES / $$$$
Tazarotene
(Do not use in pregnancy)		 Avage® Cream 0.1% 30 g Once daily at bedtime NO / $$$$


VITILIGO
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Ruxolitinib Opzelura® Cream 1.5% 60 g, 100 g Twice daily on up to 10% of body surface area. May take ≥ 24 weeks for response. NO / $$$$
Studies


WRINKLES, HYPERPIGMENTATION - COMBINATION PRODUCTS
Medication Trade name Vehicle Strength Size Dosing Generic / Price
Fluocinolone acetonide + Hydroquinone + Tretinoin Tri-Luma® Cream 0.01% / 4% / 0.05% 30 g Once daily at bedtime after washing NO / $$$


Pricing legend
  • $ = 0 - $50
  • $$ = $51 - $100
  • $$$ = $101 - $150
  • $$$$ = > $151
  • Pricing based on a 30 g/30 ml size or smallest unit sold
  • Pricing based on information from GoodRX.com®
  • Pricing may vary by region and availability